Fermentative Production of N-Alkylated Glycine Derivatives by Recombinant Corynebacterium glutamicum Using a Mutant of Imine Reductase DpkA From Pseudomonas putida

Sarcosine, an N-methylated amino acid, shows potential as antipsychotic, and serves as building block for peptide-based drugs, and acts as detergent when acetylated. N-methylated amino acids are mainly produced chemically or by biocatalysis, with either low yields or high costs for co-factor regener...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Melanie Mindt, Silvin Hannibal, Maria Heuser, Joe Max Risse, Keerthi Sasikumar, K. Madhavan Nampoothiri, Volker F. Wendisch
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-09-01
Colecção:	Frontiers in Bioengineering and Biotechnology
Assuntos:	Corynebacterium glutamicum imine reductase metabolic engineering enzyme engineering N-alkylated amino acids N-methylamino acids
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fbioe.2019.00232/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!