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SynGAP regulates protein synthesis and homeostatic synaptic plasticity in developing cortical networks.

Disrupting the balance between excitatory and inhibitory neurotransmission in the developing brain has been causally linked with intellectual disability (ID) and autism spectrum disorders (ASD). Excitatory synapse strength is regulated in the central nervous system by controlling the number of posts...

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Autori principali: Chih-Chieh Wang, Richard G Held, Benjamin J Hall
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2013-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3877118?pdf=render
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