The impact of microbiome dysbiosis on manganese-induced neurotoxicity: Brain metabolomics and multi-organ 16S rRNA profiling in mice

Manganese (Mn) is an essential metal but becomes neurotoxic upon excessive exposure. Although emerging evidence links Mn toxicity to gut microbiome alterations, little is known about how Mn affects microbial communities across multiple mucosal sites or how these changes relate to brain metabolism. T...

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Hlavní autoři:	Haitao Dong, Xueting Wang, Teng Ma, Tianzi Shan, Weifeng He, Gaoman Zhang, Zhuoran Xia, Weitong Yang, Li Chen, Piye Niu, Tian Chen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2026-03-01
Edice:	Ecotoxicology and Environmental Safety
Témata:	Manganese Neurotoxicity Microbiome dysbiosis Metabolomics Multi-organ microbiota
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S0147651326002605
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