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Efficacy of Istradefylline, an Adenosine A Receptor Antagonist, as Adjunctive Therapy to Levodopa in Parkinson’s Disease: A Pooled Analysis of 8 Phase 2b/3 Trials

Background: Istradefylline is a selective adenosine A 2A receptor antagonist for the treatment of patients with Parkinson’s disease (PD) experiencing OFF episodes while on levodopa/decarboxylase inhibitor. Objective: This pooled analysis of eight randomized, placebo-controlled, double-blind phase 2b...

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Principais autores: Robert A. Hauser, Nobutaka Hattori, Hubert Fernandez, Stuart H. Isaacson, Hideki Mochizuki, Olivier Rascol, Fabrizio Stocchi, June Li, Akihisa Mori, Yu Nakajima, Robert Ristuccia, Peter LeWitt
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publishing 2021-10-01
Serier:Journal of Parkinson’s Disease
Online adgang:https://doi.org/10.3233/JPD-212672
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