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Sphingosine-mediated death of Pseudomonas aeruginosa involves degradation of cardiolipin by the maintenance of outer lipid asymmetry system

ABSTRACT Respiratory infections with multiresistant Pseudomonas aeruginosa are a major clinical problem, affecting mainly patients with pre-existing lung diseases such as cystic fibrosis (CF) or chronic obstructive pulmonary disease but also immunocompromised or elderly patients. We have previously...

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Principais autores: Heike Grassmé, Gregory C. Wilson, Yuqing Wu, Mike Hasenberg, Simone Keitsch, Federico Caicci, Michael J. Edwards, Ildiko Szabo, Erich Gulbins
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2025-04-01
Serier:Infection and Immunity
Fag:
Pseudomonas aeruginosa
sphingosine
cardiolipin
lipase
membrane asymmetry
Mla system
Online adgang:https://journals.asm.org/doi/10.1128/iai.00591-24
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