Lymphocyte exhaustion in hepatocellular carcinoma: a dynamic evolution across disease stages

BackgroundImmune checkpoint inhibitors (ICIs) have transformed cancer therapy. However, their efficacy in hepatocellular carcinoma (HCC) is limited, highlighting the need to further explore immune microenvironments and novel biomarkers. This study examined lymphocyte populations and immune checkpoin...

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Detalles Bibliográficos

Principais autores:	Carla Fuster-Anglada, Josep Corominas, Aida Marsal, Neus Llarch, Gemma Iserte, Marco Sanduzzi-Zamparelli, Alejandro Forner, Joana Ferrer-Fábrega, Victor Holguin, Albert Morales, Carolina Saavedra, Maria Reig, Loreto Boix, Montserrat Marí, Alba Díaz
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Immunology
Assuntos:	hepatocellular carcinoma lymphocytes NK cells immune exhaustion sorafenib
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1611365/full
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