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The splicing factor YBX1 promotes the progression of osteosarcoma by upregulating VEGF165 and downregulating VEGF165b

VEGF165 and its isoform VEGF165b have the same length but opposite functions in cancer. Some studies have indicated the important role of VEGF165 in osteosarcoma (OS); however, VEGF165b has not been taken into consideration. This study aims to clarify the roles of the two isoforms in OS and the mech...

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Bibliografische Detailangaben
Hauptverfasser: Bingxuan Quan, Zhigang Li, Hongbo Yang, Shuo Li, Xiuchun Yan, Yansong Wang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2023-08-01
Schriftenreihe:Heliyon
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2405844023059145
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