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Docosahexaenoic Acid Enhances Cyclooxygenase-2 Induction by Facilitating p44/42, but Not p38, Mitogen-Activated Protein Kinase Activation in Rat Vascular Smooth Muscle Cells

The effect of docosahexaenoic acid (DHA) on cyclooxygenase expression induced by interleukin (IL)-1β and phorbol 12-myristate 13-acetate (PMA) in rat vascular smooth muscle cells (VSMCs) was investigated in order to clarify the cellular mechanism of cardiovascular protective effects. DHA and eicosap...

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Detalhes bibliográficos
Main Authors: Takuji Machida, Miho Hiramatsu, Naoya Hamaue, Masaru Minami, Masahiko Hirafuji
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2005-01-01
Colecção:Journal of Pharmacological Sciences
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1347861319321413
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