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Platelet and mitochondrial RNA is decreased in plasma-derived extracellular vesicles in women with preeclampsia—an exploratory study

Abstract Background Circulating extracellular vesicles (EVs) are increased in preeclampsia (PE) and are associated with severity and progression. We examined in this exploratory cohort study if the mRNAs and long noncoding RNAs (lncRNAs) in plasma-derived EVs were dysregulated in PE compared to norm...

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Hauptverfasser: Tove Lekva, Arvind Y.FM. Sundaram, Marie Cecilie Paasche Roland, June Åsheim, Annika E. Michelsen, Errol R. Norwitz, Pål Aukrust, Gregor D. Gilfillan, Thor Ueland
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2023-11-01
Schriftenreihe:BMC Medicine
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Online-Zugang:https://doi.org/10.1186/s12916-023-03178-x
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