Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease

Abstract Neuroinflammation is an important component of many neurodegenerative diseases, whether as a primary cause or a secondary outcome. For that reason, either as diagnostic tools or to monitor progression and/or pharmacological interventions, there is a need for robust biomarkers of neuroinflam...

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Hlavní autoři:	Marta Vicente-Rodríguez, Renzo Mancuso, Alba Peris-Yague, Camilla Simmons, NIMA Consortium, Diego Gómez-Nicola, V. Hugh Perry, Federico Turkheimer, Simon Lovestone, Christine A. Parker, Diana Cash
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2023-04-01
Edice:	Journal of Neuroinflammation
Témata:	Astrocytes CSF1R ME7 Microglia Neuroinflammation Neurons
On-line přístup:	https://doi.org/10.1186/s12974-023-02769-y
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