Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1
<p>Abstract</p> <p>Background</p> <p>β-Amyloid precursor protein (APP) has been reported to play a role in the outgrowth of neurites from cultured neurons. Both cell-surface APP and its soluble, ectodomain cleavage product (APPs-α) have been implicated in regulating the length and branching of neuri...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2008-06-01
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| Serier: | Neural Development |
| Online adgang: | http://www.neuraldevelopment.com/content/3/1/15 |
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