Wnt-presenting materials sustain H3K14-acetylation in human skeletal stem cells for tissue engineering and bone repair

Abstract Engineering functional tissues for transplantation requires insight into epigenetic mechanisms that regulate stem cell fate. We have developed the Wnt-induced osteogenic tissue model (WIOTM), a platform that recapitulates human osteogenesis, and identified acetylation of histone H3 at lysin...

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Hlavní autoři:	Pierre Becquart, Pierre Tournier, Sergi Junyent, Binbin Ma, Yu Liu, Yin Tang, Xin Chen, Dong Fang, Anjali P. Kusumbe, Shukry J. Habib
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2026-03-01
Edice:	npj Regenerative Medicine
On-line přístup:	https://doi.org/10.1038/s41536-026-00467-w
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