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HISTORY OF HEREDITARY NONPOLYPOSIS COLORECTAL CANCER OR “LYNCH SYNDROME”

Hereditary Nonpolyposis Colorectal Cancer (HNPCC or “Lynch syndrome”), involving pathogenic variants in the Mismatch Repair (MMR) genes, is the most common inherited condition that predisposed to colorectal adenomas and colorectal cancer. In this chapter I review the history of HNPCC, from early cas...

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Detalles Bibliográficos
Autor Principal: Patrick M Lynch, JD, MD
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2017-07-01
Series:Revista Médica Clínica Las Condes
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Acceso en liña:http://www.sciencedirect.com/science/article/pii/S0716864017301001
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