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Key genes and integrated modules in hematopoietic differentiation of human embryonic stem cells: a comprehensive bioinformatic analysis

Abstract Background The generation of hematopoietic stem cells (HSCs) and blood cells from human embryonic stem cells (hESCs) is a major goal for regenerative medicine; however, the differentiation mechanisms are largely undefined. Here, we aimed to identify the regulated genes and functional module...

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Main Authors: Pengfei Li, Mengyao Wu, Qiwang Lin, Shu Wang, Tong Chen, Hua Jiang
Format: Artigo
Language:Inglês
Published: BMC 2018-11-01
Series:Stem Cell Research & Therapy
Subjects:
Embryonic stem cell
Differentiation
Hematopoietic stem cell
Microarray
Online Access:http://link.springer.com/article/10.1186/s13287-018-1050-7
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