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Differentiating Drosophila female germ cells initiate Polycomb silencing by regulating PRC2-interacting proteins

Polycomb silencing represses gene expression and provides a molecular memory of chromatin state that is essential for animal development. We show that Drosophila female germline stem cells (GSCs) provide a powerful system for studying Polycomb silencing. GSCs have a non-canonical distribution of PRC...

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Autori principali: Steven Z DeLuca, Megha Ghildiyal, Liang-Yu Pang, Allan C Spradling
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications Ltd 2020-08-01
Serie:eLife
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Accesso online:https://elifesciences.org/articles/56922
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