The Dynamics of the Neuropeptide Y Receptor Type 1 Investigated by Solid-State NMR and Molecular Dynamics Simulation

We report data on the structural dynamics of the neuropeptide Y (NPY) G-protein-coupled receptor (GPCR) type 1 (Y1R), a typical representative of class A peptide ligand GPCRs, using a combination of solid-state NMR and molecular dynamics (MD) simulation. First, the equilibrium dynamics of Y1R were s...

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Autors principals:	Alexander Vogel, Mathias Bosse, Marcel Gauglitz, Sarah Wistuba, Peter Schmidt, Anette Kaiser, Vsevolod V. Gurevich, Annette G. Beck-Sickinger, Peter W. Hildebrand, Daniel Huster
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2020-11-01
Col·lecció:	Molecules
Matèries:	GPCR arrestin molecular switch NMR spectroscopy structural dynamics MD simulation
Accés en línia:	https://www.mdpi.com/1420-3049/25/23/5489
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