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Soluble CD147 regulates endostatin via its effects on the activities of MMP-9 and secreted proteasome 20S

During progression of rheumatoid arthritis (RA), angiogenesis provides oxygen and nutrients for the cells’ increased metabolic demands and number. To turn on angiogenesis, pro-angiogenic factors must outweigh anti-angiogenic factors. We have previously shown that CD147/extracellular matrix metallopr...

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Principais autores: Maya M. Rahat, Hala Sabtan, Elina Simanovich, Amir Haddad, Tal Gazitt, Joy Feld, Gleb Slobodin, Adi Kibari, Muna Elias, Devy Zisman, Michal A. Rahat
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-01-01
Serier:Frontiers in Immunology
Fag:
endostatin
CD147/EMMPRIN
MMP-9
secreted proteasome 20S
fibroblasts-monocytes interactions
angiogenesis
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1319939/full
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