Evaluation of Preexisting Anti-Hemagglutinin Stalk Antibody as a Correlate of Protection in a Healthy Volunteer Challenge with Influenza A/H1N1pdm Virus

ABSTRACT Influenza virus hemagglutinin (HA) surface glycoprotein is currently the primary target of licensed influenza vaccines. Recently, broadly reactive antibodies that target the stalk region of the HA have become a major focus of current novel vaccine development. These antibodies have been obs...

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Principais autores:	Jae-Keun Park, Alison Han, Lindsay Czajkowski, Susan Reed, Rani Athota, Tyler Bristol, Luz Angela Rosas, Adriana Cervantes-Medina, Jeffery K. Taubenberger, Matthew J. Memoli
格式:	Artigo
语言:	Inglês
出版:	American Society for Microbiology 2018-03-01
丛编:	mBio
主题:	CHIM HA stalk NA antibody human challenge influenza
在线阅读:	https://journals.asm.org/doi/10.1128/mBio.02284-17
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