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Quantitative trait and transcriptome analysis of genetic complexity underpinning cardiac interatrial septation in mice using an advanced intercross line

Unlike single-gene mutations leading to Mendelian conditions, common human diseases are likely to be emergent phenomena arising from multilayer, multiscale, and highly interconnected interactions. Atrial and ventricular septal defects are the most common forms of cardiac congenital anomalies in huma...

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Principais autores: Mahdi Moradi Marjaneh, Edwin P Kirk, Ralph Patrick, Dimuthu Alankarage, David T Humphreys, Gonzalo Del Monte-Nieto, Paola Cornejo-Paramo, Vaibhao Janbandhu, Tram B Doan, Sally L Dunwoodie, Emily S Wong, Chris Moran, Ian CA Martin, Peter C Thomson, Richard P Harvey
פורמט: Artigo
שפה:Inglês
יצא לאור: eLife Sciences Publications Ltd 2023-06-01
סדרה:eLife
נושאים:
גישה מקוונת:https://elifesciences.org/articles/83606
תגים: הוספת תג
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