Transcriptomics Guided Engineering of Exosome‐Encapsulated Bifunctional Nanosheets Targeting the Immune‐PI3K/Akt Axis for Osteoporosis Therapy

Abstract Osteoporosis, characterized by imbalanced bone metabolism and chronic inflammation, remains a therapeutic challenge due to the limitations of current single‐target therapies. This study integrates transcriptomic insights with nanomaterial engineering to develop a multi‐target strategy. Tran...

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Autors principals:	Rongze Tang, Guanhong Liu, Congcong Wang, Minghao Chao, Guangyu Ma, Pengjin Wei, Siling Du, Junjie Li, Yufan Liu, Chaonan Jing, Guoquan Wu, Ming Guan, Hongliang Chen, Fenglei Gao
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2025-12-01
Col·lecció:	Advanced Science
Matèries:	bone regeneration inflammation nanosheet osteoporosis
Accés en línia:	https://doi.org/10.1002/advs.202511327
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