Saccharomyces cerevisiae lysophospholipid acyltransferase, Lpt1, requires Asp146 and Glu297 for catalysis[S]

The esterification of lysophospholipids contributes to phospholipid synthesis, remodeling, and scavenging. Acyl-CoA-dependent lysophospholipid acyltransferase activity with broad substrate use is mediated by Saccharomyces cerevisiae Lpt1p. We sought to identify Lpt1p active site amino acids besides...

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Prif Awduron:	Paul Renauer, Nour Nasiri, Peter Oelkers
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2015-11-01
Cyfres:	Journal of Lipid Research
Pynciau:	enzymology/enzyme mechanisms phospholipids/biosynthesis phospholipids/metabolism fatty acid/transferase acyl-CoA diacylglycerol acyltransferase active site
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S0022227520354833
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