SEMA4A signaling in macrophage subpopulations and its implication in osteoarthritis

BackgroundOsteoarthritis (OA) is a common degenerative disease characterized by the deterioration of articular cartilage, affecting approximately 240 million people worldwide. Low-grade inflammation—particularly the imbalance in macrophage polarization—is a critical factor in osteoarthritis progress...

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Библиографические подробности

Главные авторы:	Yue Qiu, Shuzhong Huang, Bo Yu, Baochen Wei, Tianyu Ren, Xiaofan Yang, Zhanying Shi, Zhaolan Wei
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2026-06-01
Серии:	Frontiers in Immunology
Предметы:	macrophages osteoarthritis PLXNB2 Sema4A single-cell RNA sequencing
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1847788/full
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