Increasing Endoglin Deletion in Endothelial Cells Exacerbates the Severity of Brain Arteriovenous Malformation in Mouse

Endoglin (<i>ENG</i>) mutation causes type 1 hereditary hemorrhagic telangiectasia (HHT1). HHT1 patients have arteriovenous malformations (AVMs) in multiple organs, including the brain. In mice, <i>Eng</i> deletion induced by R26RCreER or SM22αCre leads to AVM development in the brain and other orga...

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Detalhes bibliográficos

Principais autores:	Zahra Shabani, Leandro Barbosa Do Prado, Rui Zhang, Wan Zhu, Sonali S. Shaligram, Alka Yadav, Calvin Wang, Hua Su
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2024-07-01
coleção:	Biomedicines
Assuntos:	arteriovenous malformations endothelial cells endoglin hereditary hemorrhagic telangiectasia
Acesso em linha:	https://www.mdpi.com/2227-9059/12/8/1691
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