An mDia2/ROCK signaling axis regulates invasive egress from epithelial ovarian cancer spheroids.

Multi-cellular spheroids are enriched in ascites of epithelial ovarian cancer (OvCa) patients. They represent an invasive and chemoresistant cellular population fundamental to metastatic dissemination. The molecular mechanisms triggering single cell invasive egress from spheroids remain enigmatic. m...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Krista M Pettee, Kaitlyn M Dvorak, Andrea L Nestor-Kalinoski, Kathryn M Eisenmann
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2014-01-01
Edice:	PLoS ONE
On-line přístup:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090371&type=printable
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!