Immune Responses to Gene Editing by Viral and Non-Viral Delivery Vectors Used in Retinal Gene Therapy

Inherited retinal diseases (IRDs) are a leading cause of blindness in industrialized countries, and gene therapy is quickly becoming a viable option to treat this group of diseases. Gene replacement using a viral vector has been successfully applied and advanced to commercial use for a rare group of...

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Bibliografski detalji

Glavni autori:	Duohao Ren, Sylvain Fisson, Deniz Dalkara, Divya Ail
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2022-09-01
Serija:	Pharmaceutics
Teme:	CRISPR–Cas9 Adeno-associated virus immune responses innate immune response adaptive immune response ocular gene therapy
Online pristup:	https://www.mdpi.com/1999-4923/14/9/1973
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