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Serum Pepsinogen as a Biomarker of Gastrointestinal Stromal Tumors (GIST) in Stomach

ABSTRACT Background Gastric GISTs (GG) are significant mesenchymal tumors. No biomarker has been identified for GG detection. We first observed mucosal atrophy surrounding GG tumors, leading to the hypothesis that localized atrophy may alter serum pepsinogen (PG) levels. Therefore, we developed a ma...

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Autori principali: Zhiying Gao, Laizhi Luo, Yueting Han, Yan Sun, Yonghong Huang, Shixia Li, Xingyun Chen, Huimin Yang, Zhijuan Peng, Xinyi Wang, Wei Zhao, Xi Wu, Huan Wu, Jing Bai, Wu Sun, Likun Zhou, Yi Ba
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley 2025-09-01
Serie:Cancer Medicine
Soggetti:
biomarker
gastric atrophy
GIST
serum pepsinogen
stomach
Accesso online:https://doi.org/10.1002/cam4.71186
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