Monoclonal immunoglobulin mediates complement activation in monoclonal gammopathy associated-C3 glomerulonephritis

Abstract Background C3 glomerulonephritis (C3GN) is a rare disease caused by inherited or acquired complement alternative pathway (CAP) dysregulation, which could also be secondary to monoclonal gammopathy of undetermined significance (MGUS). Herein, we described a patient presenting with C3GN and m...

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Detalhes bibliográficos

Principais autores:	Lin-Lin Li, Zhi-Ying Li, Su-Xia Wang, Xiao-Juan Yu, Ying Tan, Yu Wang, Feng Yu, Ming-Hui Zhao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2019-12-01
coleção:	BMC Nephrology
Assuntos:	C3 glomerulonephritis Anti-CFH autoantibodies Monoclonal immunoglobulin (MIg) Monoclonal gammopathy of renal significance (MGRS)
Acesso em linha:	https://doi.org/10.1186/s12882-019-1640-3
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