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Single-cell RNA-seq reveals T cell exhaustion and immune response landscape in osteosarcoma

BackgroundT cell exhaustion in the tumor microenvironment has been demonstrated as a substantial contributor to tumor immunosuppression and progression. However, the correlation between T cell exhaustion and osteosarcoma (OS) remains unclear.MethodsIn our present study, single-cell RNA-seq data for...

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Autors principals: Qizhi Fan, Yiyan Wang, Jun Cheng, Boyu Pan, Xiaofang Zang, Renfeng Liu, Youwen Deng
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2024-04-01
Col·lecció:Frontiers in Immunology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1362970/full
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