Overexpression of ONECUT1 suppresses hepatoblastoma progression via modulating tumor cell growth and tumor microenvironment

Abstract Background Hepatoblastoma is the most common malignant liver tumor in children. Our previous work showed that enforced expression of the transcription factor One Cut Homeobox 1 (ONECUT1) suppresses the initiation of hepatoblastoma. However, it remains unclear whether increasing ONECUT1 expr...

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Autors principals:	Yu Qiao, Meng Xu, Yanhui Wu, Guofei Cui, Shanshan Deng, Liangliang Bai, Xiaoshuang Song, Jian Zhong, Weijie Bian, Gang Yu, Matthias Evert, Xue Wang, Diego F. Calvisi, Xin Chen, Lin Li, Weiting Liao
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2026-04-01
Col·lecció:	Cell & Bioscience
Matèries:	Hepatoblastoma ONECUT1 Major histocompatibility complex class I CXCL16 Tumor immune microenvironment
Accés en línia:	https://doi.org/10.1186/s13578-026-01569-0
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