Radiosynthesis and Evaluation of Talazoparib and Its Derivatives as PARP-1-Targeting Agents
Poly (ADP-ribose) polymerase-1 (PARP-1) is a critical enzyme in the DNA repair process and the target of several FDA-approved inhibitors. Several of these inhibitors have been radiolabeled for non-invasive imaging of PARP-1 expression or targeted radiotherapy of PARP-1 expressing tumors. In particul...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
MDPI AG
2021-05-01
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| Seria: | Biomedicines |
| Hasła przedmiotowe: | |
| Dostęp online: | https://www.mdpi.com/2227-9059/9/5/565 |
| Etykiety: |
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