Impact of intraoperative margin optimization strategies compared to standard breast-conserving surgery on oncologic outcomes: a systematic review and meta-analysis of randomized and prospective trials

Abstract Background Achieving optimal surgical margins is critical in breast-conserving surgery (BCS) to reduce local recurrence (LR) and the need for re-excision. This meta-analysis evaluated the impact of intraoperative margin optimization strategies on key surgical and oncologic outcomes in patie...

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Autors principals:	Wajahat Mirza, Muhammad Moaz, Muhammad Sajeel Turab, Hadi Mohammad Khan, Sundus Dadan, Saeeda Yasmin, Abdullah Khan Tareen, Hamza Hanif
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-08-01
Col·lecció:	World Journal of Surgical Oncology
Matèries:	Breast-conserving surgery Intraoperative margin optimization Positive margins Re-excision rate Local recurrence Overall survival
Accés en línia:	https://doi.org/10.1186/s12957-025-03959-z
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