Whole-genome comparative analysis at the lineage/sublineage level discloses relationships between Mycobacterium tuberculosis genotype and clinical phenotype

Background Human tuberculosis (TB) caused by members of the Mycobacterium tuberculosis complex (MTBC) is the main cause of death among infectious diseases worldwide. Pulmonary TB (PTB) is the most common clinical phenotype of the disease, but some patients develop an extrapulmonary (EPTB) phenotype...

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Autors principals:	Andrea Monserrat Negrete-Paz, Gerardo Vázquez-Marrufo, Ma. Soledad Vázquez-Garcidueñas
Format:	Artigo
Idioma:	Inglês
Publicat:	PeerJ Inc. 2021-09-01
Col·lecció:	PeerJ
Matèries:	Pulmonary tuberculosis Extrapulmonary tuberculosis Drug resistance Ancient sublineages Modern sublineages SNP
Accés en línia:	https://peerj.com/articles/12128.pdf
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