Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits

Abstract Background Age-related macular degeneration (AMD) is a common condition of vision loss with disease development strongly influenced by environmental and genetic factors. Recently, 34 loci were associated with AMD at genome-wide significance. So far, little is known about a genetic overlap b...

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Bibliografski detalji

Glavni autori:	Felix Grassmann, Christina Kiel, Martina E. Zimmermann, Mathias Gorski, Veronika Grassmann, Klaus Stark, International AMD Genomics Consortium (IAMDGC), Iris M. Heid, Bernhard H. F. Weber
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2017-03-01
Serija:	Genome Medicine
Teme:	Age-related macular degeneration AMD Genetic risk scores GRS Genetic association studies Complex traits
Online pristup:	http://link.springer.com/article/10.1186/s13073-017-0418-0
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