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Comprehensive Genetic Analysis of NF2 in Sporadic Vestibular Schwannoma

ABSTRACT Objective To elucidate the genetic etiology of sporadic vestibular schwannomas (VSs) and investigate the correlation between NF2 inactivation mechanisms and preoperative clinical characteristics, including hearing function and tumor growth. Methods Nineteen patients who underwent VS resecti...

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Autores principales: Takeshi Wakabayashi, Koichiro Wasano, Kohei Nakamura, Makoto Hosoya, Ryutaro Kawano, Reika Takamatsu, Masafumi Ueno, Marie N. Shimanuki, Nobuyoshi Tsuzuki, Takanori Nishiyama, Takenori Akiyama, Masahiro Toda, Hiroshi Nishihara, Hiroyuki Ozawa, Naoki Oishi
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley 2025-10-01
Colección:Laryngoscope Investigative Otolaryngology
Materias:
clinical phenotype
comprehensive genetic analysis
NF2
somatic change
sporadic vestibular schwannoma
Acceso en línea:https://doi.org/10.1002/lio2.70265
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