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FAM96B negatively regulates FOSL1 to modulate the osteogenic differentiation and regeneration of periodontal ligament stem cells via ferroptosis

Abstract Background Periodontal ligament stem cell (PDLSC)-based therapy is one of the methods to assist bone regeneration. Understanding the functional regulation of PDLSCs and the mechanisms involved is a crucial issue in bone regeneration. This study aimed to explore the roles of the family with...

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Wedi'i Gadw mewn:
Prif Awduron: Qianyi Qin, Haoqing Yang, Runzhi Guo, Yunfei Zheng, Yiping Huang, Luyuan Jin, Zhipeng Fan, Weiran Li
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2024-12-01
Cyfres:Stem Cell Research & Therapy
Pynciau:
FAM96B
FOSL1
Periodontal ligament stem cells
Bone regeneration
Osteogenic differentiation
Ferroptosis
Mynediad Ar-lein:https://doi.org/10.1186/s13287-024-04083-7
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