Connecting signaling and metabolic pathways in EGF receptor-mediated oncogenesis of glioblastoma.

As malignant transformation requires synchronization of growth-driving signaling (S) and metabolic (M) pathways, defining cancer-specific S-M interconnected networks (SMINs) could lead to better understanding of oncogenic processes. In a systems-biology approach, we developed a mathematical model fo...

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Autors principals:	Arup K Bag, Sapan Mandloi, Saulius Jarmalavicius, Susmita Mondal, Krishna Kumar, Chhabinath Mandal, Peter Walden, Saikat Chakrabarti, Chitra Mandal
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2019-08-01
Col·lecció:	PLoS Computational Biology
Accés en línia:	https://doi.org/10.1371/journal.pcbi.1007090
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