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Identification of novel potential benzimidazole derivatives by pharmacophore generation, 3D-QSAR, virtual screening, molecular docking and ADME/ TOX analysis against breast cancer as targeted estrogen alpha receptor

Background: The estrogen alpha receptor (ERα) is critical in breast carcinogenesis. Although selective estrogen receptor modulators like tamoxifen are clinically used, their adverse effects highlight the need for safer alternatives. The study uses computational methods to identify potential ERα inhi...

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-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Aastha Sharma, Nitish Banga, Rakesh Kumar Marwaha, Balasubramanian Narasimhan
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Creative Pharma Assent 2025-04-01
Цуврал:Journal of Applied Pharmaceutical Research
Нөхцлүүд:
Онлайн хандалт:https://japtronline.com/index.php/joapr/article/view/951
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