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Striatal adenosine A2A receptor neurons control active-period sleep via parvalbumin neurons in external globus pallidus

Dysfunction of the striatum is frequently associated with sleep disturbances. However, its role in sleep-wake regulation has been paid little attention even though the striatum densely expresses adenosine A2A receptors (A2ARs), which are essential for adenosine-induced sleep. Here we showed that che...

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Principais autores: Xiang-Shan Yuan, Lu Wang, Hui Dong, Wei-Min Qu, Su-Rong Yang, Yoan Cherasse, Michael Lazarus, Serge N Schiffmann, Alban de Kerchove d'Exaerde, Rui-Xi Li, Zhi-Li Huang
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2017-10-01
Serier:eLife
Fag:
striatum
A2A receptor
sleep
chemogenetics
optogenetics
Online adgang:https://elifesciences.org/articles/29055
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