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Loss of microRNA-30a and sex-specific effects on the neonatal hyperoxic lung injury

Abstract Background Bronchopulmonary dysplasia (BPD) is characterized by an arrest in lung development and is a leading cause of morbidity in premature neonates. It has been well documented that BPD disproportionally affects males compared to females, but the molecular mechanisms behind this sex-dep...

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Principais autores: Sandra L. Grimm, Samuel Reddick, Xiaoyu Dong, Connor Leek, Amy Xiao Wang, Manuel Cantu Gutierrez, Sean M. Hartig, Bhagavatula Moorthy, Cristian Coarfa, Krithika Lingappan
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2023-08-01
coleção:Biology of Sex Differences
Assuntos:
Bronchopulmonary dysplasia
Micro-RNA
Newborn
Lung
Hyperoxia
Oxidative stress
Acesso em linha:https://doi.org/10.1186/s13293-023-00535-6
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