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Sterigmatocystin induces autophagic and apoptotic cell death of liver cancer cells via downregulation of XIAP

XIAP, or the X-linked Inhibitor of Apoptosis Protein, is the most extensively studied member within the IAP gene family. It possesses the capability to impede apoptosis through direct inhibition of caspase activity. Various kinds of cancers overexpress XIAP to enable cancer cells to avoid apoptosis....

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Principais autores: Xu Chen, Zhengping Che, Jiajia Wu, Cheng Zeng, Xiao-long Yang, Lin Zhang, Zhenghong Lin
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-04-01
Serier:Heliyon
Fag:
Apoptosis
Autophagy
Liver cancer
Sterigmatocystin
XIAP
Online adgang:http://www.sciencedirect.com/science/article/pii/S2405844024055981
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