Hyaluronic acid-coated polypeptide nanogel enhances specific distribution and therapy of tacrolimus in rheumatoid arthritis

Abstract Rheumatoid arthritis (RA) involves chronic inflammation, oxidative stress, and complex immune cell interactions, leading to joint destruction. Traditional treatments are often limited by off-target effects and systemic toxicity. This study introduces a novel therapeutic approach using hyalu...

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Detalhes bibliográficos

Principais autores:	Yuhuan Li, Xin Wang, Yu Gao, Ziyi Zhang, Te Liu, Zhuo Zhang, Yinan Wang, Fei Chang, Modi Yang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-09-01
coleção:	Journal of Nanobiotechnology
Assuntos:	Rheumatoid arthritis Reduction-responsive polypeptide nanogel Hyaluronic acid Active targeting Tacrolimus
Acesso em linha:	https://doi.org/10.1186/s12951-024-02784-y
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