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The Fungal CYP51s: Their Functions, Structures, Related Drug Resistance, and Inhibitors

CYP51 (Erg11) belongs to the cytochrome P450 monooxygenase (CYP) superfamily and mediates a crucial step of the synthesis of ergosterol, which is a fungal-specific sterol. It is also the target of azole drugs in clinical practice. In recent years, researches on fungal CYP51 have stepped into a new s...

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Detalhes bibliográficos
Principais autores: Jingxiang Zhang, Liping Li, Quanzhen Lv, Lan Yan, Yan Wang, Yuanying Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-04-01
coleção:Frontiers in Microbiology
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Acesso em linha:https://www.frontiersin.org/article/10.3389/fmicb.2019.00691/full
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