Optogenetic-mediated induction and monitoring of α-synuclein aggregation in cellular models of Parkinson’s disease

Summary: Studying Parkinson’s disease (PD) is complex due to a lack of cellular models mimicking key aspects of protein pathology. Here, we present a protocol for inducing and monitoring α-synuclein aggregation in living cells using optogenetics. We describe steps for plasmid transduction, biochemic...

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Principais autores:	Maxime Teixeira, Razan Sheta, Walid Idi, Abid Oueslati
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-12-01
Colecção:	STAR Protocols
Assuntos:	Cell Biology Microscopy Neuroscience
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2666166723007050
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