Ran promotes membrane targeting and stabilization of RhoA to orchestrate ovarian cancer cell invasion
Ran, a nucleus-cytoplasm shuttle protein, is implicated in cancer development and survival. Here, the authors show that Ran binds RhoA to impair its degradation and allow its localisation to the plasma membrane of ovarian cancer cells for tumour invasion.
-д хадгалсан:
| Үндсэн зохиолчид: | , , , , , |
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| Формат: | Artigo |
| Хэл сонгох: | Inglês |
| Хэвлэсэн: |
Nature Portfolio
2019-06-01
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| Цуврал: | Nature Communications |
| Онлайн хандалт: | https://doi.org/10.1038/s41467-019-10570-w |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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