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Intratumor heterogeneity related signature for clinical outcome and immunotherapy advantages in lung adenocarcinoma

Abstract Background Immunotherapy benefits shows discrepancy in different lung adenocarcinoma (LUAD) patients because of the intratumor heterogeneity (ITH). ITH favors tumor evolution and correlated with drug resistance. The genes mediating ITH in LUAD and their role in predicting prognosis and ther...

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Detalles Bibliográficos
Principais autores: Yanhua Zuo, Li Lin, Libo Sun
Formato: Artigo
Idioma:Inglês
Publicado: Springer 2025-03-01
Series:Discover Oncology
Assuntos:
Acceso en liña:https://doi.org/10.1007/s12672-025-02173-3
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