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Efavirenz treatment improves retinal vaso-obliteration and pathological neovascularization in a mouse model of retinopathy of prematurity

ObjectivesPrevious studies have shown the metabolic and regulatory significance of CYP46A1 in the adult retina; however, its role in the developing retina is unknown. Here, we evaluate CYP46A1 expression and the impact of its activation in the developing mouse retina under normal and pathological co...

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Bibliografiske detaljer
Principais autores: Briah Bailey, Josephine Rudd Zhong Manis, Gayatri Seth, Shubhra Rajpurohit, Allston Oxenrider, Pamela M. Martin, Ravirajsinh N. Jadeja, Menaka C. Thounaojam
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-02-01
Serier:Frontiers in Medicine
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Online adgang:https://www.frontiersin.org/articles/10.3389/fmed.2026.1745351/full
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