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A two-pronged approach to inhibit ferroptosis of MSCs caused by the iron overload in postmenopausal osteoporosis and promote osseointegration of titanium implant

Postmenopausal osteoporosis (PMOP) is a prevalent condition among elderly women. After menopause, women exhibit decreased iron excretion, which is prone to osteoporosis. To design a specific titanium implant for PMOP, we first analyze miRNAs and DNA characteristics of postmenopausal patients with an...

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Principais autores: Yulu Yang, Xianhui Zhang, Yao Yang, Pengfei Gao, Wuzhe Fan, Tao Zheng, Weihu Yang, Yu Tang, Kaiyong Cai
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Communications Co., Ltd. 2024-11-01
coleção:Bioactive Materials
Assuntos:
Postmenopausal osteoporosis
Iron overload
Ferroptosis
Caffeic acid nanosphere
Ti implant
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2452199X24002950
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