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Diversity of Immunoglobulin Light Chain Genes in Non-Teleost Ray-Finned Fish Uncovers IgL Subdivision into Five Ancient Isotypes

The aim of this study was to fill important gaps in the evolutionary history of immunoglobulins by examining the structure and diversity of IgL genes in non-teleost ray-finned fish. First, based on the bioinformatic analysis of recent transcriptomic and genomic resources, we experimentally character...

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Hlavní autoři: Sergey V. Guselnikov, Konstantin O. Baranov, Alexander M. Najakshin, Ludmila V. Mechetina, Nikolai A. Chikaev, Alexey I. Makunin, Sergey V. Kulemzin, Daria A. Andreyushkova, Matthias Stöck, Sven Wuertz, Jörn Gessner, Wesley C. Warren, Manfred Schartl, Vladimir A. Trifonov, Alexander V. Taranin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018-05-01
Edice:Frontiers in Immunology
Témata:
Acipenser ruthenus
Acipenseriformes
Polypteriformes
Holostei
evolution
immunoglobulin light chain
On-line přístup:https://www.frontiersin.org/article/10.3389/fimmu.2018.01079/full
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