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Spectroscopic insight into breast cancer: profiling small extracellular vesicles lipids via infrared spectroscopy for diagnostic precision

Abstract Breast cancer, a leading cause of female mortality due to delayed detection owing to asymptomatic nature and limited early diagnostic tools, was investigated using a multi-modal approach. Plasma-derived small EVs from breast cancer patients (BrCa, n = 74) and healthy controls (HC, n = 30) w...

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Principais autores: Abhay Mishra, Sadaqa Zehra, Prahalad Kumar Bharti, Sandeep R. Mathur, Piyush Ranjan, Atul Batra, Krishna K. Inampudi, Gyan Prakash Modi, Fredrik Nikolajeff, Saroj Kumar
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Portfolio 2024-04-01
סדרה:Scientific Reports
נושאים:
sEVs
FTIR
Spectral marker
PCA
Lipid
Proteins
גישה מקוונת:https://doi.org/10.1038/s41598-024-59863-1
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