Inhibition mechanism of the fungal β−1,3-glucan synthases by triterpenoid antifungal drugs
Abstract β−1,3-glucan synthase is the molecular target for triterpenoid and echinocandin antifungal drugs in clinical. It catalyzes the formation of β−1,3-glucan, which is the primary component of the fungal cell wall. However, the inhibition mechanism of β−1,3-glucan synthase by triterpenoid drugs...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Portfolio
2026-02-01
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| Col·lecció: | Nature Communications |
| Accés en línia: | https://doi.org/10.1038/s41467-026-69114-8 |
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